Congratulations to Adrien Labriet, Ph.D. student, for his 2nd prize for best oral presentation by a Ph.D. student for his talk given at the Scientific day of the Endo-Nephro Research Axis.
Patrick Caron and Véronique Turcotte, chemists, published with Dr Guillemette and Lévesque their novel validated method to quantify Abiraterone metabolites in plasma samples of prostate cancer patients. The paper, entitled An LC-MS/MS method for quantification of abiraterone, its active metabolites D(4)-abiraterone (D4A) and 5α-abiraterone, and their inactive glucuronide derivatives, was published in the Journal of Chromatography B. Great piece of work!
Congratulations to the research trainees in the Guillemette group who were honored at the Research day of the Faculty of Pharmacy. Adrien Labriet, Ph.D. student, 1st prize for best oral presentation by a Ph.D. student Eric Allain, Ph.D. student, 1st prize for best poster presentation by a Ph.D. student
Welcome to Jean-Philippe Emond, resident MD student and M.Sc. student, who joined the Pharmacogenomics lab under the supervision of Dr Lévesque and Guillemette.
An excellent track record for research trainees in the Guillemette group at the Research Day of the Cancer Research Center
Yannick Audet-Delage, Ph.D. student, 1st prize for Best poster presentation by a Ph.D. student
Adrien Labriet, Ph.D. student, 3rd prize for Best talk by a Ph.D. student
Joanie Vaillancourt, M.Sc. student, Best poster presentation by an M.Sc. student
Adrien Labriet, Ph.D. student, presented his most recent work at the 22nd ISSX North American meeting in Montréal, Canada. Adrien’s project was selected for an oral presentation, entitled RPL28 promoter polymorphism rs4806668 is associated with reduced survival in FOLFIRI-treated metastatic colorectal cancer patients.
Congratulations to Prof. Chantal Guillemette and Dr Eric Lévesque for their publication in collaboration with the group of Drs Paul Toren and Lawrence Klotz in Clinical Cancer Research entitled Serum sex steroids as prognostic biomarkers in patients receiving androgen deprivation therapy for recurrent prostate cancer: a post-hoc analysis of the PR.7 trial.
Eric Allain, Ph.D. student, published his first paper on his Ph.D. project in Annals of Hematology entitled: Sex-dependent association of circulating sex steroids, pituitary hormones and treatment-free survival in patients with chronic lymphocytic leukemia. This study was conducted in collaboration with the research team of Prof. Katrina Vanura, Medical University of Vienna, Austria.
Eric also presented his work at the AACR Annual meeting 2018, held in Chicago.
Congratulations to Patrick Caron, chemist, and Chantal Guillemette for their work in collaboration with Michael B. Cook’s team, NIH, published in the Journal of the National Cancer Institute entitled Associations between Prediagnostic Levels of Circulating Sex Steroid Hormones and Esophageal/Gastric Cardia Adenocarcinoma.
Great news for Adrien Labriet, Ph.D. student: Adrien was awarded a highly competitive Graduate student scholarship from the Fonds de recherche du Québec – Santé (FRQS) to pursue his Ph.D. project. Congratulations!
Adrien‘s work on colorectal cancer conducted in collaboration with the group of Dr Giuseppe Toffoli, CRO Aviano, Italy, was published in Frontiers in Pharmacology, entitled: Association of STAT-3 rs1053004 and VDR rs11574077 with FOLFIRI-related gastrointestinal toxicity in metastatic colorectal cancer patients.
Congratulations to Yannick Audet-Delage, Ph.D. student: Yannick received a travel award from the Metabolomics Society to attend the AACR annual meeting 2018.
Yannick presented his recent work at the AACR, entitled Metabolomics biomarkers for endometrial cancer and its recurrence after surgery in postmenopausal women.
This study was also published in Frontiers in Endocrinology, 9:87
Yannick also published in the Journal of Steroids and Biological Molecular Biology a second paper on his work on endometrial cancer entitled Estradiol Metabolites as Biomarkers of Endometrial Cancer Prognosis After Surgery.
Very well done Yannick!
Joanie Vaillancourt, M.Sc. student, was awarded a Hydro-Québec excellence scholarship, for the Faculty of Pharmacy. Good news Joanie!
The Guillemette’s group published novel findings on alternative variants of the main hepatic UGT2B10. Congratulations to Adrien Labriet, PhD student, and colleagues for their publication Posttranscriptional regulation of UGT2B10 hepatic expression and activity by alternative splicing in Drug Metabolism and Disposition.
Congratulations to Adrien Labriet, Ph.D. student. Adrien was awarded the 1st prize for best poster presentation at the Scientific Day of the Endocrinology-Nephrology Axis, CHU de Québec.
Great achievements for the research trainees in the Guillemette group at the Research Day of the Faculty of Pharmacy:
Yannick Audet-Delage, Ph.D. student, 1st prize for best talk by a Ph.D. student
Adrien Labriet, Ph.D. student, 1st prize for best poster presentation by a Ph.D. student
Eric Allain, Ph.D. student, 2nd prize for best poster presentation by a Ph.D. student
Sophie Anne Blanchet, summer student, 1st prize for best poster presentation by honors student
Congratulations to all!
Congratulations to Eric Allain, Ph.D. student, for his George D. Smith Award received at the 13th Canadian CLL meeting in recognition for his excellence in CLL Research as a trainee.
Eric presented his most recent work in a talk entitled: Sex-dependent association of circulating hormones and treatment-free survival in patients with CLL
The Ph.D candidate, Adrien Labriet, published his first paper with us in Frontiers Pharmacology, entitled:
He presented this work at the 21st North American ISSX Meeting held in Providence, USA. http://www.issx2017na.com
Dre Guillemette has been awarded $638,775 CND from CIHR for a 5-year research project entitled: Function of the glucuronosyltransferase pathway in chronic lymphocytic leukemia. This work will be conducted in collaboration with Dr Éric Lévesque.
Please view recent interviews given by Dr Chantal Guillemette and two of her graduate students (Eric Allain and Camille Girard-Bock), Faculty of Pharmacy, Laval University, about the research in the Pharmacogenomics group (in french).
Congratulations to Adrien Labriet, Ph.D. student, for winning the best poster presentation award at the Journées de la Recherche, Endocrinology-Nephrology axis, CHU de Québec.
Welcome to Joanie Vaillancourt, a new M.Sc. student in the Pharmacogenomics lab under the supervision of Dr Guillemette. Joanie was awarded a highly competitive studentship from the Fonds de recherché Santé-Québec. Congratulations Joanie!
Quantitative profiling of the UGT transcriptome in human drug metabolizing tissues by Tourancheau A, Rouleau M, Milena-Guauque S, Villeneuve L, Gilbert I, Droit A, Guillemette C. Published in The Pharmacogenomics Journal.
The complex UGT alternative splicing programs have the strong potential to contribute to interindividual variability in drug metabolism in addition to diversify the UGT proteome.
Rouleau M, Audet-Delage Y, Desjardins S, Rouleau M, Girard-Bock C, Guillemette C. Endogenous protein interactome of human UDP-glucuronosyltransferases exposed by untargeted proteomics. Published in Frontiers in Pharmacology.
Our work provides unprecedented evidence for a functional interaction between glucuronidation and other metabolic pathways.
Audet-Delage Y, Rouleau M, Rouleau M, Roberge J, Miard S, Picard F, Têtu B and Guillemette C. Cross-talk between alternatively spliced UGT1A isoforms and colon cancer cell metabolism. Published in Molecular Pharmacology. Great job!