Welcome to the Pharmacogenomics Laboratory web site.

Research themes: Improving drug treatments and prognostic tools

Recent Lab News

Congratulations to Adrien Labriet, Ph.D. student. Adrien was awarded the 1st prize for best poster presentation at the Scientific Day of the Endocrinology-Nephrology Axis, CHU de Québec.

Great achievements for the research trainees in the Guillemette group at the Research Day of the Faculty of Pharmacy:

Yannick Audet-Delage, Ph.D. student, 1st prize for best talk by a Ph.D. student

Adrien Labriet, Ph.D. student, 1st prize for best poster presentation by a Ph.D. student

Eric Allain, Ph.D. student, 2nd prize for best poster presentation by a Ph.D. student

Sophie Anne Blanchet, summer student, 1st prize for best poster presentation by honors student

Congratulations to all!

Congratulations to Eric Allain, Ph.D. student, for his George D. Smith Award received at the 13th Canadian CLL meeting in recognition for his excellence in CLL Research as a trainee.

Eric presented his most recent work in a talk entitled: Sex-dependent association of circulating hormones and treatment-free survival in patients with CLL

The Ph.D candidate, Adrien Labriet, published his first paper with us in Frontiers Pharmacology, entitled:

Improved progression-free survival in metastatic colorectal cancer patients carriers of the HNF1A coding variant p.I27L treated with irinotecan

He presented this work at the 21st North American ISSX Meeting held in Providence, USA. http://www.issx2017na.com

Dre Guillemette has been awarded $638,775 CND from CIHR for a 5-year research project entitled: Function of the glucuronosyltransferase pathway in chronic lymphocytic leukemia.  This work will be conducted in collaboration with Dr Éric Lévesque.

Please view recent interviews given by Dr Chantal Guillemette and two of her graduate students (Eric Allain and Camille Girard-Bock), Faculty of Pharmacy, Laval University, about the research in the Pharmacogenomics group (in french).



Congratulations to Adrien Labriet, Ph.D. student, for winning the best poster presentation award at the Journées de la Recherche, Endocrinology-Nephrology axis, CHU de Québec.

Welcome to Joanie Vaillancourt, a new M.Sc. student in the Pharmacogenomics lab under the supervision of Dr Guillemette. Joanie was awarded a highly competitive studentship from the Fonds de recherché Santé-Québec. Congratulations Joanie!

Quantitative profiling of the UGT transcriptome in human drug metabolizing tissues by Tourancheau A, Rouleau M, Milena-Guauque S, Villeneuve L, Gilbert I, Droit A, Guillemette C. Published in The Pharmacogenomics Journal.

The complex UGT alternative splicing programs have the strong potential to contribute to interindividual variability in drug metabolism in addition to diversify the UGT proteome.

Rouleau M, Audet-Delage Y, Desjardins S, Rouleau M, Girard-Bock C, Guillemette C. Endogenous protein interactome of human UDP-glucuronosyltransferases exposed by untargeted proteomics. Published in Frontiers in Pharmacology.

Our work provides unprecedented evidence for a functional interaction between glucuronidation and other metabolic pathways.

Audet-Delage Y, Rouleau M, Rouleau M, Roberge J, Miard S, Picard F, Têtu B and Guillemette C. Cross-talk between alternatively spliced UGT1A isoforms and colon cancer cell metabolism. Published in Molecular Pharmacology. Great job!

Congratulations to Camille Girard-Bock, Marie-Odile Benoit-Biancamano, Lyne Villeneuve, Sylvie Desjardins and Chantal Guillemette for their publication in Drug Metabolism and Disposition entitled “A rare UGT2B7 variant creates a novel N-glycosylation site at codon 121 with impaired enzyme activity”.

Congratulations to Adrien Labriet and Yannick Audet-Delage, Ph.D. students in the Pharmacogenomics group. Adrien and Yannick each won the 1st prize in their respective group for best poster presentation by a Ph.D. student at the 16th Journée de la Recherche, Faculty of Pharmacy, Laval University.

Eric Allain, Ph.D. student was awarded the Excellence studentship Fernand Labrie from Desjardins Research and Innovation studentship/Fondation CHU de Québec. Congratulations Eric!

Congratulations to Eric Allain, Ph.D. student, for winning the George D. Smith Award 2nd place at the 12th Canadian CLL meeting in recognition for his excellence in CLL Research as a trainee.

Congratulations to the Pharmacogenomics research group for publishing their recent work revealing the expansion of the UGT transcriptome and diversification of UGT functions in human tissues, in Cell Reports (http://www.cell.com/cell-reports/abstract/S2211-1247(16)31173-1).

This publication was highlighted in the September 29, 2016 issue of the Fil des Événements, Laval University



The Leukemia and Lymphoma Society of Canada recently held their fund-raising campagn in Québec city. Dr Chantal Guillemette (second from left), Dr Eric Lévesque and Ph.D. student Eric Allain (not on this picture) were actively involved in the LIGHT THE NIGHT’WALK.


Congratulations to Eric Allain, Ph.D. student, for his Jury Award for Best PhD student poster presentation at the CRC Student Scientific Day 2016, Laval University.

Sandra Guauque-Olarte, post-doctoral fellow in the Pharmacogenomics research group, has taken a Professor-Researcher position in the Faculty of Dentistry at the Universidad Cooperativa de Colombia (Pasto). Congratulations Sandra!

Adrien Labriet, Ph.D. student, was awarded a studentship from the Fonds de l’enseignement et de la recherche (Laval University). Great news Adrien!

Yannick Audet-Delage, Ph.D. student, received a travel award from the Metabolomics Society to attend the Informatics and Statistics for Metabolomics workshop.

Eric Allain, Ph.D. student, was selected to receive a registration award to attend the Bioinformatics for Cancer Genomics workshop.

Welcome to Laurence Cambron-Fortin! Laurence, an experienced bioanalyst, joined the metabolomics group of the Pharmacogenomics Laboratory.

Anais Belledant completed her Ph.D. studies with a solid thesis defense.  Congratulations Dr Belledant for your work and your Ph.D. degree, we wish you all the best with your future projects and career.