UGT2B15 allele nomenclature (view change log)

Allele naming	Protein	Nucleotide change	Amino acid change	Effect	Enzyme activity		Genbank	References	Notes
					In vivo	In vitro
UGT2B15*1	UGT2B15.1			Wild-type	Normal	Normal	A48633	Chen et al
UGT2B15*2	UGT2B15.2	253(G>T)	D^85Y		Decreased clearance of lorazepam (Chung et al, 2005) and oxazepam (He et al, BrJClinPhar, In press 2009)	Increased activity on androgens (Levesque et al) Decreased glucuronidation of oxazepam (Court et al. 2004 )	N/A	Levesque et al
UGT2B15*3	UGT2B15.3	256(T>C)	L^86S				N/A	Tomboc et al
UGT2B15*4	UGT2B15.4	1568(A>C)	K^523T				N/A	Court et al. 2004
UGT2B15*5	UGT2B15.5	253(G>T)/1568(A>C)	D^85Y/K^523T				N/A	Court et al. 2004
UGT2B15*6	UGT2B15.6	1055(C>T)	T^352I				N/A	Court et al. 2004
UGT2B15*7	UGT2B15.7	1055(C>T)/1568(A>C)	T^352I/K^523T				N/A	Gaedigk, unpublished

N/A : data not available in the manuscript

Changes made on the last update are in red (2010-12-21).