UGT1A7 allele nomenclature (view change log)

Allele naming	Protein	Promoter nucleotide change	Coding nucleotide change	Amino acid change	Effect	Enzyme activity		Genbank	References	Notes
						In vivo	In vitro
UGT1A7*1a	UGT1A7.1				Wild-type		High	AF297093
UGT1A7*1b	UGT1A7.1	-70(G>A)							Saeki et al. 2006
UGT1A7*2	UGT1A7.2		387(T>G)/391(C>A)/392(G>A)	N129K/R131K			High (Guillemette et al. 2000)	AF110191	Guillemette et al. 2000
UGT1A7*3	UGT1A7.3		387(T>G)/391(C>A)/392(G>A)/ 622(T>C)	N129K/R131K/W208R			Low (Guillemette et al. 2000)	AF110192	Guillemette et al. 2000
UGT1A7*4	UGT1A7.4		622(T>C)	W208R			Low (Guillemette et al. 2000)	AF110193	Guillemette et al. 2000
UGT1A7*5	UGT1A7.5		343(G>A)	G115S			Low (Villeneuve et al. 2003)	AF434903	Villeneuve et al. 2003
UGT1A7*6	UGT1A7.6		417(G>C)	E139D			High (Villeneuve et al. 2003)	AF434904	Villeneuve et al. 2003
UGT1A7*7	UGT1A7.7		387(T>G)/391(C>A)/392(G>A)/417(G>C)	N129K/R131K/E139D			High (Villeneuve et al. 2003)	AF436810	Villeneuve et al. 2003
UGT1A7*8	UGT1A7.8		387(T>G)/391(C>A)/392(G>A)/417(G>C)/622(T>C)	N129K/R131K/E139D/W208R			Low (Villeneuve et al. 2003)	AF461758	Villeneuve et al. 2003
UGT1A7*9	UGT1A7.9		343(G>A)/387(T>G)/391(C>A)/392(G>A)	G115S/N129K/R131K			Low (Villeneuve et al. 2003)	AF502567	Villeneuve et al. 2003
UGT1A7*10	UGT1A7.10		386(A>G)/387(T>G)/391(C>A)/392(G>A)/622(T>C)	N129R/R131K/W208R				N/A	van der Logt et al. 2004
UGT1A7*11	UGT1A7.11		392(G>A)	R131Q					Verlaan et al. 2005
UGT1A7*12	UGT1A7.12	-57(T>G)	622(T>C)/760(C>T)	W208R/R254X			70 % reduction of luciferase activity		Thomas et al. 2005 Lankisch et al. 2005
UGT1A7*13	UGT1A7.13		828(C>A)	N276K					Thomas et al. 2005
UGT1A7*14	UGT1A7.14		422(G>C)	C141S					Fujita et al. 2006

Changes made on the last update are in red (2007-09-04).

N/A : data not available in the manuscript