UGT1A4 allele nomenclature (view change log)

Allele naming	Protein	Nucleotide change	Amino acid change	Effect	Enzyme activity		Genbank	References	Notes
					In vivo	In vitro
UGT1A4 *1a	UGT1A4.1	Reference sequence (AF297093)		Wild-type	Normal	Normal	AF297093
UGT1A4*1b	UGT1A4.1	471(C>T)	C^157C	Silent			N/A	Saeki M, 2005
UGT1A4*1c	UGT1A4.1	-219(C>T)/-163(G>A)/448(T>C)/804(G>A)/IVS1+43(C>T)	L^150L/P^268P				N/A	Saeki M, 2005
UGT1A4*1d	UGT1A4.1	IVS1+101(G>T)					N/A	Saeki M, 2005
UGT1A4*1e	UGT1A4.1	30(G>A)	P^10P	Silent			N/A	Saeki M, 2005
UGT1A4*1f	UGT1A4.1	357(T>C)	N^119N	Silent			N/A	Saeki M, 2005
UGT1A4*1g	UGT1A4.1	-217(T>G)					N/A	Saeki M, 2005
UGT1A4*1h	UGT1A4.1	-36(G>A)					N/A	Saeki M, 2005
UGT1A4*1i	UGT1A4.1	IVS1+98(A>G)					N/A	Saeki M, 2005
UGT1A4*2	UGT1A4.2	70(C>A)	P^24T			Substrate-dependent (Ehmer et al., 2004; Wiener et al., 2004)	N/A	Wiener D, 2004
UGT1A4*3a	UGT1A4.3	-219(C>T)/-163(G>A)/142(T>G)	L^48V				N/A	Wiener D, 2004
UGT1A4*3b	UGT1A4.3	142(T>G)	L^48V			Low activity (Ehmer et al. 2004)	N/A	Saeki M, 2005
UGT1A4*4	UGT1A4.4	31(C>T)	R^11W				N/A	Saeki M, 2005
UGT1A4*5	UGT1A4.5	127delA/142(T>G)	43fsX22	Frameshift – early stop codon			N/A	Saeki M, 2005
UGT1A4*6	UGT1A4.6	175delG/325(A>G)	59fsX6	Frameshift – early stop codon			N/A	Saeki M, 2005
UGT1A4*7	UGT1A4.7	-219(C>T)/-163(G>A)/142(T>G)/271(C>T)/448(T>C)/804(G>A)/IVS1+43(C>T)	L^48V/R^91C/L^150L/P^268P				N/A	Saeki M, 2005
UGT1A4*8	UGT1A4.8	IVS1+1(G>T)		Splicing defect			N/A	Saeki M, 2005

N/A : data not available in the manuscript